Circadian Rhythms: Impact on Mental Health

Topic: Healthcare Research
Words: 2311 Pages: 8

The human body is characterized by a unique biological clock that dictates a wide range of responses, behaviors, and emotions. This cyclical mechanism takes place in the background and usually occurs in recurrent 24-hour cycles. The process controls human sleep-wake patterns, thereby being able to dictate any individual’s overall wellbeing and health. The totality of these internal processes and their ability to regulate mood and emotion are referred to as circadian rhythms. Some practices have the potential to disorient this mechanism and trigger additional psychological and biological problems, such as sleep deprivation and consumption of caffeine. Since circadian rhythms control biological processes, such as sleep and alertness, disruptions can trigger psychological and mental health problems that call for personalized treatment plans or therapies.

Circadian Rhythms: Background and Description

Modern scholars have been keen to study and analyze human behaviors and learn more about internal biological processes that influence them. Boiko et al. (2022) describe such 24-hour cycles as circadian rhythms that support essential functions in living organisms. The wake-sleep cycle is an outstanding example of such mechanisms in human beings. The brain acts as a master clock that reads existing cues in the surrounding environment, such as darkness and sunlight. Panagiotou et al. (2019) argues that a properly synchronized rhythm will allow human beings to experience restorative, healthy, and consistent sleep. Individuals who fail to get adequate sleep might record various challenges, such as insomnia and depression.

The relationship between biological clocks and most of the natural processes is an area that continues to attract attention of many scholars. For example, Panagiotou et al. (2019) observe that responses to seasonal changes in plants cannot be described as circadian rhythms since they do not occur within 24 hours. In another study, Xu et al. (2021) indicated that the presence of sunlight triggered the brain to generate and distribute signals of alertness. Consequently, the ensuing mechanism allowed the targeted individual to experience activeness and wakefulness. Darkness triggers the production of a compound or hormone known as melatonin (Boiko et al., 2022). Its occurrence in the body promotes sleepiness, thereby allowing individuals to remain asleep for a long time. A stable cycle emerges that is capable of allowing people to engage in meaningful and productive activities throughout the day.

Recent studies have gone further to reveal that circadian rhythms in the body tend to affect other systems and biological processes. For example, Xu et al. (2021) indicated that a unique relationship existed between metabolism and the integrity of such cycles. Consequently, emerging rhythms could have significant impacts on the level of cholesterol, blood glucose, and emotions. The impact of circadian rhythms on the human immune system and its ability to prevent terminal diseases in human beings has become an important area for additional research. The emerging insights can guide more people to address a wide range of medical challenges and eventually lead better lives.

Mental health remains one of the critical fields associated with circadian rhythms in human beings. For instance, individuals who fail to get adequate sleep or interfere with this biological process will increase their chances of developing depression. Most of the affected people might report cases of bipolar disorder, emotional instability, and possible development of various neuro-generative medical challenges (Farhud & Aryan, 2018). Dementia stands out as a good example of diseases that could arise due to disturbed circadian rhythms. Prolonged disruptions on the 24-hour sleep cycle could trigger the development of obstructive sleep apnea (OSA). When this rhythm remains disoriented or misaligned, the affected individual might sleep excessively during the day and record poor overall health.

Current Research and Treatment

Sleep deprivation remains a common challenge many people encounter in their lives. This problem is directly linked to the changing economic models, lifestyles, and social exchange. Irrespective of the specified cause of insufficient sleep, its occurrence is capable of triggering numerous medical challenges (Xu et al., 2021). Past epidemiological analyses have shown conclusively that individuals who sleep for short periods within every 24-hour cycle will report various negative experiences. This issue can increase chances of developing obesity and diabetes. When these health concerns remain untreated or unmanaged, chances are high that the affected person might increase his or her chances of developing cardiovascular disease.

Loss of sleep contributes to negative impacts on various biological attributes and processes. Such an occurrence disorients amino acid, lipid, and carbohydrate metabolism in the human body. These developments affect or trigger unexpected changes in circadian modulation and the manner in which the related cycles take place. Recent analyses have gone further to examine the role of genes in determining the nature of circadian rhythms in the body. Specifically, Panagiotou et al. (2019) indicate that genetic mechanisms are usually capable of functioning optimally depending on the recorded food intake, sleep-wake cycle, and activity. The totality of these processes can have significant impacts on the transcriptome, thereby triggering unexpected challenges.

Any form of disturbance or disorientation in the circadian system is capable of affecting the optimal functioning of biomarkers. Such compounds will dictate how human beings perform in a number of areas, including behavior, mental processes, and emotions. In another study, Xu et al. (2021) observed that a lack of adequate sleep during the night affected a person’s cognition and mood. Additional problems included poor immune processes and disoriented metabolism. In the same study, it occurred that individuals who completed their professional duties in shifts or those who experienced jetlag reported imbalanced circadian rhythms (Xu et al., 2021). The recorded outcome was directly linked with physiological and neurological challenges, thereby making it impossible for the brain to function optimally.

Disruptions in circadian rhythmicity remain a major challenge whereby sleep-wake processes tend to be affected. Emerging mood disorders will trigger antidepressant impacts on the human brain, thereby changing the process of secreting melatonin. In advanced cases, individuals who become stressed will experience additional problems with emotions and memory. A person’s level of aggression, anxiety, or fatigue might increase significantly. Most of the MRI research conducted in the past has presented similar insights to show conclusively that a unique relationship exists between the brain and mood (Xu et al., 2021). This knowledge is essential towards shedding more light on these cycles and how they affect a person’s health outcomes.

The presented insights show conclusively that any form of alteration in the 24-hour circadian rhythm has the potential to affect sleep. A wide range of triggers in the environment will dictate the manner in which the body produces melatonin. Such a compound is essential since it promotes prolonged sleep during the night. Any form of interference will affect the process and eventually contribute significantly to sleep loss. In some cases, people’s career fields and activities could compel them to engage in strenuous roles that can eventually result in prolonged periods of alertness (Ruby et al., 2018). Under such circumstances, the affected individuals will be unable to coordinate and pursue their goals more efficiently.

In extreme cases, body systems that fail to function optimally will eventually put the circadian rhythm off. In such a situation, the disturbed sleep-wake mechanism will disorient the sleeping process. Under such circumstances, the affected individual will be unable to get adequate sleep during the day. The possible outcome is that the overall quality of sleep will decrease significantly, thereby affecting the individual’s ability to engage in productive activities (Ruby et al., 2018). As described earlier, the nature of these issues will increase chances of recording OSA. This sleep disorder triggers lapses in breathing patterns, thereby affecting the overall process of metabolism (Walker et al., 2020). These conditions have been directly associated with additional problems, such as insomnia, sleepiness during the day, fatigue, and poor mental health.

For centuries, human beings have used caffeine to manipulate sleep and their mental states. Ruby et al. (2018) indicate that the addictive product has the potential to restore wakefulness for a short period while improving task performance. Some people rely on the compound as one of the best approaches to deal with sleep deprivation. Bisdounis et al. (2022) went further to indicate that individuals who relied on caffeine to become more productive had higher chances of disorienting their circadian rhythms. In extreme cases, most of the affected people might report cases of withdrawal and eventually be unable to complete a wide range of tasks. In another study, Faulkner et al. (2019) observed that people who consumed caffeine during the evening delayed their overall circadian rhythms. Such an outcome was possible due to the fact that the compound delayed the production of melatonin.

While caffeine is associated with increased energy and alertness, some analysts have gone further to describe its possible impacts on long-term sleep patterns. For instance, Reichert et al. (2022) reported that individuals who relied on this substance to get rid of sleep affected their long-term circadian patterns. Specifically, majority of them were unable to sleep adequately or in an orderly manner within every 24-hour period. These observations show conclusively that caffeine was capable of altering or impacting the major genetic compounds and molecules that were responsible for guiding and supporting circadian clocks and subsequent rhythms. Prolonged periods of sleep loss led to subsequent reduction in the genes that supported the circadian amplitude (Panagiotou et al., 2019). Consequently, the affected individuals will experience additional challenges, such as OSA, depression, and overall poor mental health.

The nature of the described issues is directly linked to the development of circadian rhythm sleep problems or disorders. These conditions are characterized by poor sleep patterns whereby individuals find it hard to lead high-quality lives. Individuals experiencing any of the common disorders will experience a number of symptoms. For example, Panagiotou et al. (2019) indicate most of the patients will develop insomnia and take long before they can wake up. In extreme cases, some people might suffer from depression and be unable to complete their tasks diligently. Some will encounter unique challenges when trying to establish meaningful social relations or complete their obligations. These problems explain why there is a need for every affected individual to seek the much-needed treatment.

Psychiatrists and medical experts can apply divergent treatment options depending on the symptoms a specific patient reports. First, behavioral therapy is a recommended approach whereby specialists guide people to develop sustainable sleep patterns, avoid naps, and consider the importance of exercises. The approach will discourage the consumption of compounds capable of disorienting sleep, such as nicotine, caffeine, and even alcohol (Panagiotou et al., 2019). Bright light therapy (BLT) has emerged as a new approach whereby individuals could be guided to restore their 24-hour sleep circadian rhythms (Faulkner et al., 2019). Therapists can expose this kind of light to patients in the morning and reduce its intensity in the evening to induce sleep. The affected individuals should remain committed to ensure that desirable results are eventually recorded.

On top of the outlined therapeutic techniques, proper medications exist to ensure that more people are able to deal with sleep deprivation. Melatonin and wake-inducing substances are capable of supporting the treatment of this condition. Tasimelteon is a common drug indicated in persons with OSA (Schmitz et al., 2022). The guidance of professionals in the field of psychiatry is recommendable to ensure that the patients take the right doses. Chronotherapy is another technique whereby individuals with severe OSA receive timely support. The individual needs to remain committed if they are to shift and balance their natural cycles of wakefulness and sleep. These treatment methods are, therefore, appropriate and capable of supporting the changing health needs of more patients.

Relevance of Circadian Rhythms in Everyday Life

The studied topic is of great importance since it examines an area that past analysts and scholars have not taken seriously. The emerging insights can guide more people to consider the best ways to improve their circadian rhythms and avoid disruptors, such as caffeine. The presented observation has the potential to guide more people to understand when they are suffering from sleep deprivation. This understanding will allow them to relate the symptoms with the described aspects (Boiko et al., 2022). Individuals who become less productive due to the challenge of sleep deprivation will be able to reconsider their sleep-wake circadian rhythms and examine what could have gone wrong. The emerging knowledge will guide them to apply the most appropriate behavioral and lifestyle interventions. This practice will make it easier for them to improve their emotions and be in a position to deal with mood disorders.

Many people experience a number of situations in their daily lives that are directly linked to this topic. For instance, jetlags, working conditions, and diseases have the potential to disorient the natural circadian cycle. This occurrence could additional challenges, such as depression, fatigue, and OSA. Without proper knowledge, the affected patients might focus on medications that cannot treat the real causal factor. This topic, therefore, becomes relevant towards guiding individuals and psychiatrists to focus on the existing challenges and consider the best ways to deal with sleep deprivation (Ke et al., 2022). This analysis offers additional insights for guiding people to take caffeine sparingly and seek personalized treatment whenever they develop insomnia and depression related to sleep loss.

In conclusion, circadian rhythms are powerful mechanisms that are informed by biological clocks in living organisms. Any form of disturbance on these 24-hour cycles will significantly affect the mental health and wellbeing of the affected people. This problem has the potential to trigger sleep loss, thereby triggering additional health problems that could affect the overall quality of life. Some of the major conditions arising from a disoriented circadian rhythm include insomnia, depression, and OSA. This topic is of great importance since it links sleep deprivation to caffeine use and the possibility of triggering psychological challenges. The emerging ideas provide detailed treatment plans that could be adopted to improve people’s sleep patterns and eventually make them more productive in their lives.

References

Bisdounis, L., Saunders, K. E. A., Farley, H. J., Lee, C. K., McGowan, N. M., Espie, C. A., & Kyle, S. D. (2022). Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: A systematic review of randomised controlled trials. Neuroscience & Biobehavioral Reviews, 132(2), 378-390. Web.

Boiko, D. I., Skrypnikov, A. M., Shkodina, A. D., Hasan, M. M., Ashraf, G. M., & Rahman, M. H. (2022). Circadian rhythm disorder and anxiety as mental health complications in post-COVID-19. Environmental Science and Pollution Research, 29, 28062–28069. Web.

Farhud, D., & Aryan, Z. (2018). Circadian rhythm, lifestyle and health: A narrative review. Iran Journal of Public Health, 47(8), 1068-1076. Web.

Faulkner, S. M., Bee, P. E., Meyer, N., & Dijk, D., & Drake, R. J. (2019). Light therapies to improve sleep in intrinsic circadian rhythm sleep disorders and neuro-psychiatric illness: A systematic review and meta-analysis. Sleep Medicine Reviews, 46, 108-123. Web.

Ke, P., Zheng, C., Liu, F., Wu, L. J., Tang, Y., Wu, Y., Lv, D., Chen, H., Qian, L., Wu, X., & Zeng, K. (2022). Relationship between circadian genes and memory impairment caused by sleep deprivation. PeerJ, 10, 1-22. Web.

Panagiotou, M., Meijer, M., Meijer, J. M., & Deboer, T. (2019). Effects of chronic caffeine consumption on sleep and the sleep electroencephalogram in mice. Journal of Psychopharmacology, 33(1), 122–131. Web.

Reichert, C. F., Deboer, T., & Landolt, H. (2022). Adenosine, caffeine, and sleep–wake regulation: State of the science and perspectives. Journal of Sleep Research, 31(4), 1-21. 10. Web.

Ruby, C. L., Verbanes, N. M., Palmer, K. N., Zisk, C. F., Bunion, D. J., & Marinos, L. N. (2018). Caffeine delays light-entrained activity and potentiates circadian photic phase-resetting in mice. Journal of Biological Rhythms, 33(5), 523-534. Web.

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