Alternative Drug Treatment of Patients to Address the Issue of Pathophysiology

Topic: Healthcare Research
Words: 307 Pages: 1

People with bipolar disorder change their mood: from feeling extremely happy or elevated (manic) or incredibly low and depressed. Mood swings can last from a few days to months or even years and affect people’s thinking, functioning, and daily activities (Perrotta, 2019). Medical history and treatment history are essential for further medication not to harm the patient’s health. Therefore, the right decision was to analyze and conduct research before prescribing new drugs. At the beginning of treatment, it is necessary to provide the patient with walks in the fresh air, peace, communication with family and friends, positive emotions, and avoidance of stressful situations (Gordovez & McMahon, 2020). These actions will help to reduce the manifestations of unstable behavior naturally.

Lithium should be the main drug for mood stabilization because it effectively treats and gives positive results in patients. However, it is necessary to increase the dose of the medicine for the patient so that the daily rate of mood stabilizer was 1000 milligrams or 1 gram. For the basic treatment from a group of antipsychotics of the second generation at detection of acute mania, it is necessary to appoint Aripiprazole, namely 15-30 milligrams a day (Haggarty & Perlis, 2021). The drug will help reduce the manifestations of the manic phase of bipolar disorder.

For the patient’s mood to remain stable and normal, it is necessary to change the treatment to the drug Amitriptyline, which is taken orally, initially twenty-five milligrams three times a day. If the drug is ineffective, the dose should gradually increase to one hundred and fifty milligrams per day. The antidepressant effect develops within two to four weeks after taking the drug (Kato, 2019). After the patient’s discharge, antipsychotics should be taken in a maintenance dose. The dose will be selected for the patient individually depending on the drug’s effectiveness and the patient’s condition.


Gordovez, F.J., & McMahon, F.J. (2020). The genetics of bipolar disorder. Molecular Psychiatry, 25(3), 544–559.

Haggarty, S.J., & Perlis,R. H. (2021). Advances toward precision medicine for bipolar disorder: Mechanisms & molecules. Molecular Psychiatry, 26(1), 168–185.

Kato, T. (2019). Current understanding of bipolar disorder: Toward integration of biological basis and treatment strategies. Psychiatry and Clinical Neurosciences, 73(9), 526–540. Web.

Perrotta, G. (2019). Bipolar disorder: Definition, differential diagnosis, clinical contexts and therapeutic approaches. Journal of Neuroscience and Neurological Surgery, 5(1), 2–6.

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